SEEC - surface-enhanced ellipsometric contrast microscopy




SEEC Microscopy is the only technique to provide the visualization and the mapping of nanometric samples in air and in water:

- in real-time
- without any labeling
- with a sub-micrometric lateral resolution (<300nm)

These main features make the SEEC Microscopy a powerful and perfectly adapted technique for the live characterization of any organic and biological samples.
Sarfus HR and LR Stations are based on SEEC Technology.
Based on high-quality optical devices, the SARFUS HR station is the high-resolution SEEC system. Imaging and topographic analyses of samples down to the nanoscale can be performed in dry and in liquid. High-quality images and accurate data acquistion are offered with this robust and calibrated optical system.
The Sarfus HR station enables measurement with a Z-limit of detection down to 0.1nm and an accuracy better than 0.3nm in dry and 0.2nm in liquid.
The SARFUS LR Station instead is an entry-level system dedicated to routine analysie in dry. Imaging and topographic characterization of nanometric samples are. The system offered Z-limit of detection better than 2nm and measurement accuracy better than 2nm.The SARFUS LR Station is the perfect tool for rapid and precise analyses for samples with thickness higher to 2nm. Nanometric films, nanopatterns, Langmuir-Blodgett films, liquid crystal and coating are some exemples of samples studiable by the Sarfus LR stations.

Main features
- Flexible mode of analysis, in static or dynamic mode, in air or in water
- High-resolution imaging
- High-sensitivity analysis
- Access to sample topography
- Real-time analysis
- Label-free technique

Main applications
- Live visualization of nanolayer, biofilm, biochip, ...
- Topographic analysis of nanometric films and patterns.
- Real-time study of molecular adsorption and desorption.
- Real-time study of (bio)films build-up and degradation.
- Kinetics studies of film morphological change vs. time, T°, ...
- Control of the homogeneity of thin films/patterns.
- Visualization of the nano-objects dispersion.
- Live visualization of nano-objects/biological layers interaction.
- Visualization of vesicles spreading on surface.
- Characterization of swelling effect.
- Studies of extra-cellular matrix.